The Biotech Startups Podcast
🧬 Purpose-Driven Innovation: Building Teams to Solve Biotech Problems | Bogdan Knezevic (Part 3/4)
May 5, 2025
"Until you experience a thing, you don’t know a thing. That’s something that bothers me a lot with the investor world-unless you’ve done it, you don’t really know what the grind feels like." In this episode, Bogdan Knezevic, co-founder and CEO of Kaleidoscope, unpacks how hands-on experience-from the grind at Frequency Therapeutics to launching the Rhodes Incubator-shaped his passion for biotech startups and team building. He shares the pivotal role of serendipity and authentic networking at Creative Destruction Lab and Entrepreneur First, which ultimately set the stage for founding Kaleidoscope. Bogdan dives into the challenges of innovating biotech R&D infrastructure, the importance of collaboration, and why tackling meaningful problems drives his mission in a rapidly evolving industry.
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"Until you experience a thing, you don’t know a thing. That’s something that bothers me a lot with the investor world-unless you’ve done it, you don’t really know what the grind feels like."

In this episode, Bogdan Knezevic, co-founder and CEO of Kaleidoscope, unpacks how hands-on experience-from the grind at Frequency Therapeutics to launching the Rhodes Incubator-shaped his passion for biotech startups and team building. 

He shares the pivotal role of serendipity and authentic networking at Creative Destruction Lab and Entrepreneur First, which ultimately set the stage for founding Kaleidoscope. Bogdan dives into the challenges of innovating biotech R&D infrastructure, the importance of collaboration, and why tackling meaningful problems drives his mission in a rapidly evolving industry.

Key topics covered:


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Find our guest, Bogdan Knezevic, at these links: 
LinkedIn: https://www.linkedin.com/in/bogdanknezevic/
Website: https://www.kaleidoscope.bio/
 
Find our host, Jon Chee, at these links: 
LinkedIn: https://www.linkedin.com/in/jonchee

Learn more about Excedr:
LinkedIn: https://www.linkedin.com/company/excedr/ 
Website: https://www.excedr.com

Intro & Outro Songs Created by OkKyojin, Owned by Excedr:
Website: https://flow.page/kyojin 

Resources & Articles:
Biotech Fundraising Milestones Resource: https://blog.kaleidoscope.bio/biotech-milestones-for-effective-fundraising/
Exhalation: Stories: https://www.goodreads.com/book/show/41160292-exhalation
Stories of Your Life and Other: https://www.goodreads.com/book/show/223380.Stories_of_Your_Life_and_Others

Companies, Universities, & People mentioned:
Kaleidoscope Bio: https://www.kaleidoscope.bio/
Creative Destruction Lab: https://creativedestructionlab.com/
Entrepreneur First: https://www.joinef.com/

Ahmed Elnaiem: https://www.linkedin.com/in/aelnaiem/
David Yen: https://www.linkedin.com/in/david-y-e-n/
Matt Clifford: https://www.linkedin.com/in/mattcliffordef/?originalSubdomain=uk

Timestamps:
00:00 Intro
02:00 Discovering a love for startups at Frequency Therapeutics
06:13 Launching the Rhodes Incubator and learning what makes teams work
08:01 Gaining startup know-how through student-run organizations
10:51 Building strong co-founder bonds and the value of team chemistry
13:38 Leading the AI stream at Creative Destruction Lab
17:31 Embracing serendipity and authentic networking
20:00 Helping launch Entrepreneur First’s Toronto program
22:35 Committing to start Kaleidoscope with longtime friends
25:41 Defining Kaleidoscope’s purpose and picking meaningful problems
29:34 Tackling biotech’s digital transformation and leaving paper behind
31:13 Shaping the future of biotech with next-gen product vision
34:55 Outro

The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.