The Genetics Podcast
EP 170: Pan-European collaboration and dementia research with Angela Bradshaw, from Alzheimer Europe
January 16, 2025
This week on The Genetics Podcast, Patrick is joined by Angela Bradshaw, Director for Research at Alzheimer Europe and honorary lecturer at the University of Glasgow. Patrick and Angela discuss coordinating the dementia research efforts of more than 30 countries, the enormous heterogeneity of dementia and Alzheimer’s disease, the future of potential new gene therapies, and the critical role of advocacy organizations for patient communities.
0:00 Intro to The Genetics Podcast

01:50 Welcome to Angela and how she joined Alzheimer Europe

05:38 The biggest priorities and areas of focus for dementia and Alzheimer’s Disease (AD) research

09:42 Biomarkers for dementia and how early in disease development they can be utilized

12:12 The heterogeneity of dementia and AD and current understanding of subtypes and treatment journeys

16:07 The challenges of diagnosis, early identifiers, and the integration of genetics

19:15 Angela’s view on the latest breakthrough therapies

23:43 Coordinating dementia research efforts across 30+ European countries

28:48 Reimbursement frameworks and shared regulations across different countries

33:10 Angela’s thoughts on the near future of gene therapies for AD and dementia

37:35 Why Angela spent 50 hours traveling the length of Australia by bus

41:10 Closing remarks

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