Frame by Frame: Rethink Imaging
Why All Medicine is Educated Guessing with Dr. Ehsan Samei (Re-release)
June 17, 2025
In this episode of the Frame by Frame: Rethink Imaging podcast, Chris St John revisits his conversation with Dr. Ehsan Samei, Chief Imaging Physicist at Duke University on the balance between scientific precision and clinical judgment in medical imaging. They explore why medicine is still a sophisticated “guessing game,” how AI enhances rather than replaces human expertise, and why the future of diagnostics depends on harmonizing data with patient-centered care. If you enjoyed this episode, subscribe and leave us a review! It really helps in reaching more like-minded enthusiasts.
In this episode of Frame by Frame: Rethink Imaging, host Chris St John revisits Dr. Ehsan Samei, Duke University's Chief Imaging Physicist, to explore the nuanced intersection of quantitative analytics and human judgment in the field of medical imaging.

Dr. Samei shares his unique perspective on how imaging combines the exactness of physics and data science with the subtle art of interpretation, shedding light on why even the most advanced technologies require human oversight. 

From the philosophy behind diagnostic uncertainty to the evolving role of AI in radiology, the conversation spans critical themes such as patient-centered care, diagnostic accuracy, and the future of medical expertise.

If you enjoyed this episode, subscribe and leave us a review! It really helps in reaching more like-minded enthusiasts!

What You'll Learn:

Chapters:

[00:00] Intro: The Art and Science of Medical Imaging
[02:13] From Physics to Medicine: A Journey into Medical Imaging
[04:06] Bridging Certainty and Uncertainty in Healthcare
[09:17] The Challenge of Patient-Specific Care and Data
[17:10] Evolution of Medical Imaging: Beyond Looking Inside
[24:26] Quantitative vs Qualitative: Finding the Balance
[27:59] AI and Human Judgment in Medical Interpretation
[31:27] Measuring Success in Medical Imaging
[38:02] Future of Healthcare: Merging Humanity with Technology
[41:42] Final Thoughts: The Path Forward in Medical Imaging


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