The Biotech Startups Podcast
🧬 Cyriac Roeding - Part 4 | Revolutionizing Cancer Detection & Therapy | Harnessing Synthetic Biology to Reshape Diagnostics | Solving Biotech’s Toughest Problems
January 9, 2025
Part 4 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide.
Part 4 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. 

Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups.

In this episode, you’ll hear about:


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Find Our Guest, Cyriac Roeding, at these links: 
https://www.linkedin.com/in/cyriacroeding/
https://www.earli.com/ 
https://www.joinrewind.com/ 

Find Our Host, Jon Chee, at these links: 
https://www.linkedin.com/in/jonchee
https://www.excedr.com

Excedr Socials & Website
LinkedIn: https://www.linkedin.com/company/excedr/ 
Youtube: https://www.youtube.com/@excedr 
Instagram: https://www.instagram.com/excedr_inc 
Twitter: https://twitter.com/ExcedrInc 
Facebook: https://www.facebook.com/excedr 
TikTok: https://www.tiktok.com/@excedr 
Podcast Website: https://www.thebiotechstartupspodcast.com/ 

Enriched Notes:

Topics Mentioned:
Earli: https://www.earli.com/ 
Stanford University: https://www.stanford.edu/
Andreessen Horowitz: https://a16z.com/
Marc Benioff: https://www.linkedin.com/in/marcbenioff/
Khosla Ventures: https://www.khoslaventures.com/
Lab Equipment List, Synthetic Biology Research: https://www.excedr.com/blog/lab-equipment-list-for-synthetic-biology-research
How to Bootstrap Your Biotech Startup & Scale: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup
When & How to Pivot a Biotech Startup: https://www.excedr.com/blog/when-how-to-pivot-a-biotech-startup
How to Craft a Pitch Deck for Biotech Investors: https://www.excedr.com/resources/how-to-craft-a-pitch-deck-for-biotech-investors
Top VC Firms for Biotech in 2024: https://www.excedr.com/blog/top-vc-firms-for-biotech
Biotech Startup Support Resources: https://www.excedr.com/resources-category/biotech-startup-support

People Mentioned:
Dr. Sam Gambhir: https://en.wikipedia.org/wiki/Sanjiv_Sam_Gambhir
David Suhy: https://www.linkedin.com/in/davidsuhy/
Jorge Conde: https://www.linkedin.com/in/jorge-conde-4099225/
Jim Allison: https://faculty.mdanderson.org/profiles/james_allison.html
Pam Sharma: https://faculty.mdanderson.org/profiles/padmanee_sharma.html
Phil Greenberg: https://www.fredhutch.org/en/faculty-lab-directory/greenberg-philip.html

Timestamps:
00:00 Intro
02:08 How a Thanksgiving article about Dr. Sam Gambhir inspired Earli’s founding
05:43 Meeting Dr. Gambhir and learning biology as a non-scientist entrepreneur
09:02 Discovering the “one idea” that led to Earli’s revolutionary synthetic biology approach
12:54 Earli’s mission to transform cancer detection and diagnostics
17:30 Overcoming major challenges and achieving breakthroughs in diagnostics accuracy
21:54 The emotional and scientific legacy of Dr. Gambhir and its impact on Earli’s vision
26:28 Earli’s innovative approach to bridging diagnostics and therapeutics
30:05 The business potential of Earli’s platform for cancer and other diseases
33:04 Cyriac’s advice on taking the road less traveled as an entrepreneur
35:41 Outro

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