How did Indigenous Amazonian cultures discover the extraordinary chemistry behind ayahuasca long before Western science understood how it worked? In the mini episode of Masters of the Mind, host Alexandre Tomic sits down with neuroscientist, pharmacologist and author Dr. Andrew Gallimore to explore the history of ayahuasca, from Richard Spruce's encounters in the Amazon to William Burroughs' search for the brew's missing ingredient. The conversation reveals how combining two plants creates a pharmacological effect that neither plant produces in the same way alone, and how this centuries-old knowledge connects to modern research into endogenous DMT.

Ayahuasca, DMT and the science behind one of pharmacology's most fascinating mysteries. How did Indigenous Amazonian cultures develop a brew containing DMT when the molecule alone does not produce the same effects when taken orally? Dr. Andrew Gallimore explores the chemistry, history and scientific discoveries behind ayahuasca. In this mini episode of Masters of the Mind, host Alexandre Tomic speaks with Gallimore about Indigenous plant knowledge, monoamine oxidase inhibitors, the history of scientific discovery and the connections between traditional pharmacology and modern research into endogenous DMT. Subscribe to Masters of the Mind for weekly mini episodes exploring neuroscience, psychedelics, consciousness and the nature of reality.

What if the most extraordinary thing about DMT is the possibility that we still don't understand what people are experiencing? In the debut episode of Masters of the Mind, host Alexandre Tomic sits down with neuroscientist, pharmacologist and author Dr. Andrew Gallimore to explore the science of DMT, the mystery of psychedelic entity encounters and the possibility that our everyday experience of reality tells us less than we think. From the forgotten history of ayahuasca to extended DMT experiences, emerging neuroscience and the search for nonhuman intelligence, this conversation asks some uncomfortable questions about consciousness, perception and the limits of scientific explanation.

What if consciousness is stranger than we ever imagined? In the debut episode of Masters of the Mind, Alexandre Tomic sits down with Dr. Andrew Gallimore to explore DMT, ancient intelligence, the brain's construction of reality and the science of extended psychedelic experiences. Listen to the trailer for a glimpse of a conversation that stretches from neuroscience and pharmacology to some of the biggest questions about the nature of reality. Subscribe and follow Masters of the Mind for weekly mini episodes and future conversations. #MasterOfTheMind #AndrewGallimore #DMT #Consciousness #Psychedelics